Name :
INTS7 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
INTS7 Rabbit Polyclonal antibody. Positive WB detected in HEK-293 cells, A431 cells. Positive IF detected in SH-SY5Y cells. Positive IHC detected in human brain tissue. Observed molecular weight by Western-blot: 107kd
Tested applications :
ELISA, WB, IHC, IF
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
C1orf73 antibody; DKFZp434B168 antibody; INT7 antibody; integrator complex subunit 7 antibody; INTS7 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of INTS7 recombinant protein (Accession Number: NM_001199811). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200IF: 1:20-1:200
Background :
INTS7 is a subunit of the integrator complex. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Plays a role in DNA damage response (DDR) signaling during the S phase (PMID: 21659603).
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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