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Name :
INTS8 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
INTS8 Rabbit Polyclonal antibody. Positive IF detected in Hela cells. Positive WB detected in MCF7 cells, HeLa cells. Positive IP detected in HeLa cells. Observed molecular weight by Western-blot: 90-115 kDa

Tested applications :
ELISA, WB, IF, IP

Species reactivity :
Human; other species not tested.

Alternative names :
C8orf52 antibody; FLJ20530 antibody; INT8 antibody; integrator complex subunit 8 antibody; INTS8 antibody; Protein kaonashi 1 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of Peptide (Accession Number: NM_017864). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:1000IP: 1:200-1:2000IF: 1:10-1:100

Background :
INTS8, also named as C8orf52, is a Component of the Integrator complex which is a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3′-box-dependent processing. INTS8 is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel