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Name :
Involucrin antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
Involucrin Rabbit Polyclonal antibody. Positive WB detected in Raji cells, NIH/3T3 cells. Positive IHC detected in human skin tissue, human oesophagus tissue. Observed molecular weight by Western-blot: 80-90kd or 56-70kd

Tested applications :
ELISA, WB, IHC

Species reactivity :
Human, Mouse; other species not tested.

Alternative names :
involucrin antibody; IVL antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of Peptide (Accession Number: NM_005547). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200

Background :
IVL, also named as involucrin, belongs to the involucrin family. It is a part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia. This antibody is specific to IVL.

References :
Mu Y, Zhou H, Wu WJ, Hu LC, Chen HB. Dynamic expression of miR-206-3p during mouse skin development is independent of keratinocyte differentiation. Molecular medicine reports. 12(6):8113-20. 2015.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel