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Name :
IPO4 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
IPO4 Rabbit Polyclonal antibody. Positive IF detected in HepG2 cells. Positive IHC detected in human colon cancer tissue. Positive IP detected in mouse testis tissue. Positive WB detected in HeLa cells, human brain tissue, mouse testis tissue. Observed molecular weight by Western-blot: 118kd

Tested applications :
ELISA, WB, IHC, IF, IP

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
FLJ23338 antibody; Imp4 antibody; Imp4b antibody; importin 4 antibody; Importin 4b antibody; IPO4 antibody; Ran binding protein 4 antibody; RanBP4 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of IPO4 recombinant protein (Accession Number: BC003690). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:200-1:2000IHC: 1:20-1:200IF: 1:10-1:100

Background :
IPO4 represents importin 4

References :
Echeverría PC, Bernthaler A, Dupuis P, Mayer B, Picard D. An interaction network predicted from public data as a discovery tool: application to the Hsp90 molecular chaperone machine. PloS one. 6(10):e26044. 2011. Wang J, Sarkar TR, Zhou M. CCAAT/enhancer binding protein delta (C/EBPdelta, CEBPD)-mediated nuclear import of FANCD2 by IPO4 augments cellular response to DNA damage. Proceedings of the National Academy of Sciences of the United States of America. 107(37):16131-6. 2010. Humbert MC, Weihbrecht K, Searby CC. ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting. Proceedings of the National Academy of Sciences of the United States of America. 109(48):19691-6. 2012.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel