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Name :
IRGM Polyclonal Antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
Polyclonal antibody to IRGM

Tested applications :
WB, IHC

Species reactivity :
Human, Mouse, Rat

Alternative names :
IRGM antibody; IFI1 antibody; IRGM1 antibody; LRG-47 antibody; LRG47 antibody; immunity related GTPase M antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
Antigen: A synthetic peptide of human IRGM

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide, pH7.3.

Storage instructions :
Store at 4℃. Avoid freeze / thaw cycles.

Applications :
WB 1:500 – 1:1000IHC 1:20 – 1:50

Background :
Putative GTPase which is required for clearance of acute protozoan and bacterial infections. Functions in innate immune response probably through regulation of autophagy. May regulate proinflammatory cytokine production and prevent endotoxemia upon infection. May also play a role in macrophages adhesion and motility (By similarity).

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel