Name :
ITPA antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
ITPA Rabbit Polyclonal antibody. Positive IF detected in MCF-7 cells. Positive IHC detected in human heart tissue, human lung cancer tissue. Positive IP detected in mouse liver tissue. Positive WB detected in K-562 cells, HeLa cells, HT-1080 cells, human liver tissue, mouse heart tissue, mouse liver tissue, NIH/3T3 cells, rat liver tissue. Observed molecular weight by Western-blot: 22 kDa
Tested applications :
ELISA, WB, IF, IHC, IP
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
C20orf37 antibody; dJ794I6.3 antibody; HLC14 06 P antibody; Inosine triphosphatase antibody; ITPA antibody; ITPase antibody; OK/SW cl.9 antibody
Immunogen :
Human ITPA Recombinant protein (GST tag)
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of ITPA recombinant protein (Accession Number: NM_033453). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:500-1:5000IHC: 1:20-1:200IF: 1:10-1:100
Background :
ITPA(Inosine triphosphate pyrophosphatase) catalyzes the pyrophosphohydrolysis of inosine triphosphate (ITP) to inosine monophosphate (IMP).It expresses in the cytoplasm(PMID:11278832).It can be detected a band of 44 Kda as a homodimer in the western blot(PMID:19631656) though its predictedsize is 21kd.This protein has two isforms with the molecular weight of 20KDa and 21KDa.
References :
Herting G, Barber K, Zappala MR, Cunningham RP, Burgis NE. Quantitative in vitro and in vivo characterization of the human P32T mutant ITPase. Biochimica et biophysica acta. 1802(2):269-74. 2010. Gall AD, Gall A, Moore AC. Analysis of human ITPase nucleobase specificity by site-directed mutagenesis. Biochimie. 95(9):1711-21. 2013.
Related websites: https://www.medchemexpress.com/antibodies.html
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