Name :
ITPKC antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
ITPKC Rabbit Polyclonal antibody. Positive IF detected in HepG2 cells. Positive IHC detected in human skeletal muscle tissue, human heart tissue, human lymphoma tissue. Positive WB detected in human heart tissue. Positive IP detected in HepG2 cells. Observed molecular weight by Western-blot: 100-105 kDa
Tested applications :
ELISA, WB, IF, IHC, IP
Species reactivity :
Human; other species not tested.
Alternative names :
InsP 3 kinase C antibody; IP3 3 kinase C antibody; IP3K C antibody; IP3KC antibody; ITPKC antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of ITPKC recombinant protein (Accession Number: XM_047439466). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IP: 1:200-1:1000IHC: 1:20-1:200IF: 1:20-1:200
Background :
ITPKC(Inositol-trisphosphate 3-kinase C) is also named as IP3KC and belongs to the inositol phosphokinase (IPK) family. It can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate and is relatively weakly activated by the calcium-calmodulin complex. ITPKC also acts as a negative regulator of T-cell activation through the Ca(2+)/NFAT signaling pathway, and the C allele may contribute to immune hyperreactivity in Kawasaki disease(PMID:17160344).
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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