Name :
ITPR1 Polyclonal Antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Polyclonal antibody to ITPR1
Tested applications :
WB, IF
Species reactivity :
Human, Mouse, Rat
Alternative names :
ITPR1 antibody; ACV antibody; CLA4 antibody; INSP3R1 antibody; IP3R antibody; IP3R1 antibody; PPP1R94 antibody; SCA15 antibody; SCA16 antibody; SCA29 antibody; inositol 1,4,5-trisphosphate receptor type 1 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1100-1250 of human ITPR1 (NP_001161744.1).
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage instructions :
Store at -20℃. Avoid freeze / thaw cycles.
Applications :
WB 1:500 – 1:2000IF 1:50 – 1:200
Background :
Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1 (By similarity). Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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