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Name :
IVD antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
IVD Mouse Monoclonal antibody. Positive WB detected in Hela cells, HEK-293 cells, human liver tissue, Jurkat cells, MCF7 cells, Transfected HEK-293 cells. Positive IHC detected in human liver tissue. Positive IF detected in Hela cells, MCF-7 cells. Observed molecular weight by Western-blot: 43kD

Tested applications :
ELISA, WB, IHC, IF

Species reactivity :
Human; other species not tested.

Alternative names :
ACAD2 antibody; IVD antibody

Immunogen :
Human IVD Recombinant protein (His tag)

Isotype :
Mouse IgG2a

Preparation :
This antibody was obtained by immunization of IVD recombinant protein (Accession Number: NM_002225). Purification method: Protein A purified.

Clonality :
Monoclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200IF: 1:10-1:100

Background :
IVD(Isovaleryl CoA dehydrogenase, mitochondrial) is a member of the acylCoA dehydrogenase family and is involved in the catabolism of leucine. In size, IVD precursor and mature proteins produced by class I mutants are indistinguishable from their normal counterparts. Class II, III, and IV mutants make IVD precursor proteins 42 kD in size rather than the normal 45 kD(PMID:2063866). It has 2 isoforms produced by alternative splicing.

References :
Liu H, Zhang H, Cui R, Guo X, Wang D, Dai J. Activation of peroxisome proliferator-activated receptor α ameliorates perfluorododecanoic acid-induced production of reactive oxygen species in rat liver. Archives of toxicology. 2015.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel