Name :
JAM3 Polyclonal Antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Polyclonal antibody to JAM3
Tested applications :
WB
Species reactivity :
Human
Alternative names :
JAM3 antibody; JAM-2 antibody; JAM-3 antibody; JAM-C antibody; JAMC antibody; junctional adhesion molecule C antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
Antigen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human JAM3 (NP_116190.3).
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage instructions :
Store at -20℃. Avoid freeze / thaw cycles.
Applications :
WB 1:500 – 1:2000
Background :
Mediates cell-cell adhesion. Functions as counter-receptor for JAM2. Functions as a counter-receptor for ITGAM, mediating leukocyte-platelet interactions and is involved in the regulation of transepithelial migration of polymorphonuclear neutrophils (PMN). Plays a role in angiogenesis. May play a role in the regulation of cell migration (Probable). Required for normal polarization and acrosome formation in developing spermatids, and for normal male fertility (By similarity).; Soluble form of JAM-C: Promotes chemotaxis of vascular endothelial cells and stimulates angiogenesis.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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