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Name :
JP45/JSRP1 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
JP45/JSRP1 Rabbit Polyclonal antibody. Positive IHC detected in human pancreas cancer tissue. Positive WB detected in human skeletal muscle tissue. Observed molecular weight by Western-blot: 30kd

Tested applications :
ELISA, IHC, WB

Species reactivity :
Human; other species not tested.

Alternative names :
FLJ32416 antibody; JP 45 antibody; JP45 antibody; JP45/JSRP1 antibody; JSRP1 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of JP45/JSRP1 recombinant protein (Accession Number: NM_144616). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200

Background :
JSRP1 (Junctional sarcoplasmic reticulum protein 1), also known as JP-45, is an integral protein of the junctional face membrane of the skeletal muscle sarcoplasmic reticulum (SR), and interacts with calsequestrin and the skeletal-muscle dihydropyridine receptor Cav1. JP-45 is an important protein for functional expression of voltage-dependent calcium channels. Involvement of JP-45 in the molecular mechanism underlying skeletal muscle excitation-contraction coupling has been reported. Although the predicated molecular weight of JP-45 is 36 kDa, it appears a 45-kDa band in western blotting in most cases.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel