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Name :
Kallikrein 11 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
Kallikrein 11 Rabbit Polyclonal antibody. Positive WB detected in MCF7 cells, HeLa cells, PC-3 cells, Y79 cells. Positive IHC detected in human prostate cancer tissue, human brain tissue. Positive IF detected in PC-3 cells. Observed molecular weight by Western-blot: 40kd

Tested applications :
ELISA, WB, IHC, IF

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
Hippostasin antibody; hK11 antibody; Kallikrein 11 antibody; KLK11 antibody; PRSS20 antibody; Serine protease 20 antibody; TLSP antibody; Trypsin like protease antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of Kallikrein 11 recombinant protein (Accession Number: NM_001136032). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200IF: 1:10-1:100

Background :
KLK11(Kallikrein-11) is also named as PRSS20, TLSP and belongs to the peptidase S1 family and Kallikrein subfamily. It is a multifunctinal protease cleaving several substrates for kallikrein and trypsin and involved in normal physiology processes in bronchus. This full length protein has a signal peptide, a propeptide and four glycosylation sites. It has 4 isoforms produced by alternative splicing with the molecular weight of 31 kDa, 27 kDa,34 kDa and 30 kDa.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel