Name :
KCNB1-Specific antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
KCNB1-Specific Rabbit Polyclonal antibody. Positive IF detected in SH-SY5Y cells, HEK-293 cells.
Tested applications :
ELISA, IF
Species reactivity :
Human; other species not tested.
Alternative names :
DRK1 antibody; h DRK1 antibody; KCNB1 antibody; KV2.1 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of Peptide (Accession Number: NM_004975). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: IF: 1:10-1:100
Background :
KCNB1, also named as DRK1, KV2.1, and h-DRK1, belongs to the potassium channel family and B (Shab) subfamily. KCNB1 mediates the voltage-dependent potassium ion permeability of excitable membranes. Channels open or close in response to the voltage difference across the membrane, letting potassium ions pass in accordance with their electrochemical gradient. The antibody is specific to KCNB1.
References :
Liu W, Wang D, Song K. Inhibition of 15-lipoxygenase (15-LOX) reverses hypoxia-induced down-regulation of potassium channels Kv1.5 and Kv2.1Inhibition of 15-lipoxygenase (15-LOX) reverses hypoxia-induced down-regulation of potassium channels Kv1.5 and Kv2.1. International journal of clinical and experimental medicine. 7(11):4147-53. 2014.
Related websites: https://www.medchemexpress.com/antibodies.html
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