Name :
KHSRP antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
KHSRP Rabbit Polyclonal antibody. Positive IF detected in HeLa cells. Positive IHC detected in human testis tissue. Positive WB detected in HeLa cells, Jurkat cells. Observed molecular weight by Western-blot: 75kd
Tested applications :
ELISA, WB, IHC, IF
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
FBP2 antibody; FUBP2 antibody; FUSE binding protein 2 antibody; KHSRP antibody; KSRP antibody; p75 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of Peptide (Accession Number: NM_003685). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200IF: 1:20-1:200
Background :
KHSRP, also named as FUBP2, KSRP and p75, belongs to the KHSRP family. It binds to the dendritic targeting element and may play a role in mRNA trafficking. KHSRP is a part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. It mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. KHSRP may interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. It is involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3′-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.
References :
Chai F, Li HY, Wang W. Subcellular quantitative proteomic analysis reveals host proteins involved in human cytomegalovirus infection. Biochimica et biophysica acta. 1854(8):967-78. 2015. Jiang H, Zhang J, Du Y. microRNA-185 modulates low density lipoprotein receptor expression as a key posttranscriptional regulator. Atherosclerosis. 243(2):523-32. 2015.
Related websites: https://www.medchemexpress.com/antibodies.html
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