Name :
KISS1 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
KISS1 Rabbit Polyclonal antibody. Positive WB detected in NIH/3T3 cells, human placenta tissue, mouse brain tissue. Positive IF detected in NIH/3T3 cells. Positive IHC detected in human lung cancer tissue. Observed molecular weight by Western-blot: 16-20 kDa
Tested applications :
ELISA, WB, IHC, IF
Species reactivity :
Human, Mouse; other species not tested.
Alternative names :
KiSS 1 antibody; KiSS 1 metastasis suppressor antibody; KISS1 antibody; Kisspeptin 1 antibody; Metastasis suppressor KiSS 1 antibody; metastin antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of KISS1 recombinant protein (Accession Number: NM_002256). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:1000IHC: 1:20-1:200IF: 1:20-1:200
Background :
KISS1, also known as kisspeptin, is a metastasis suppressor protein that suppresses metastases of human melanomas and breast carcinomas without affecting tumorigenicity. It may regulate events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A C-terminally amidated peptide of KISS1, metastin (kisspeptin-54 or kp-54), functions as the endogenous ligand of the G-protein coupled receptor GPR54 (PMID: 11457843; 11385580). KISS1-GPR54 signaling is involved in the regulation of reproduction, playing an important role in initiating secretion of gonadotropin-releasing hormone (GnRH) at puberty (PMID: 18753370).
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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