Name :
KLF10 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
KLF10 Rabbit Polyclonal antibody. Positive IF detected in HeLa cells. Positive WB detected in HeLa cells, Jurkat cells. Positive IP detected in Jurkat cells. Observed molecular weight by Western-blot: 52 kDa
Tested applications :
ELISA, WB, IF, IP
Species reactivity :
Human; other species not tested.
Alternative names :
EGR alpha antibody; EGRA antibody; KLF10 antibody; Krueppel like factor 10 antibody; Kruppel like factor 10 antibody; TIEG antibody; TIEG 1 antibody; TIEG1 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of KLF10 recombinant protein (Accession Number: NM_001032282). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:1000IP: 1:200-1:1000IF: 1:20-1:200
Background :
KLF10 (Krueppel-like factor 10), also known as TIEG1, is a transcription factor that plays a role in the regulation of cell growth. It binds to the consensus sequence 5′-GGTGTG-3′. KLF10 plays a role in the response to TGFbeta (through the TGFbeta/Smad signalling pathway) and estrogen. In both cases, KLF10 induces or repressed gene transcription to enhance the TGFbeta/Smad signalling pathway, as well as other pathways, to regulate cell proliferation, differentiation and apoptosis. KLF10 has been shown to have a role in skeletal disease (osteopenia/osteoporosis), hypertrophic cardiomyopathy, and breast and prostate cancer.This antibody is a rabbit polyclonal antibody raised against a full-length human KLF10 protein, and specifically recognizes the 52kd KLF10 protein.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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