Name :
KLF12 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
KLF12 Rabbit Polyclonal antibody. Positive WB detected in Raji cells, HepG2 cells, human kidney tissue. Observed molecular weight by Western-blot: 65 kDa
Tested applications :
ELISA, WB
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
AP 2rep antibody; AP2REP antibody; HSPC122 antibody; KLF12 antibody; Krueppel like factor 12 antibody; Kruppel like factor 12 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of KLF12 recombinant protein (Accession Number: NM_001400139). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000
Background :
KLF12, also named as AP2REP or HSPC122, is a 402 amino acid protein, which contains three C2H2-type zinc fingers and belongs to the Sp1 C2H2-type zinc-finger protein family. KLF12 localizes in the nucleus and confers strong transcriptional repression to the AP-2-alpha gene. KLF12 is atranscriptional silencer to the AP2-alpha gene, mediating positive and negative regulation of the AP2-A expression trhough a set of overlapping cis-regulatory promoters elements.
References :
Shen X, Hu Y, Jiang Y. Krüppel-like factor 12 negatively regulates human endometrial stromal cell decidualization. Biochemical and biophysical research communications. 433(1):11-7. 2013.
Related websites: https://www.medchemexpress.com/antibodies.html
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