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Name :
KPNA1 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
KPNA1 Rabbit Polyclonal antibody. Positive IF detected in HepG2 cells, MCF-7 cells. Positive IHC detected in human testis tissue, human kidney tissue, human ovary tissue, human placenta tissue. Positive IP detected in HEK-293 cells. Positive WB detected in K-562 cells, HepG2 cells, Jurkat cells. Observed molecular weight by Western-blot: 60 kDa

Tested applications :
ELISA, WB, IHC, IF, IP

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
Importin subunit alpha 1 antibody; IPOA5 antibody; Karyopherin subunit alpha 1 antibody; KPNA1 antibody; Nucleoprotein interactor 1 antibody; RAG cohort protein 2 antibody; RCH2 antibody; SRP1 antibody; SRP1 beta antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of KPNA1 recombinant protein (Accession Number: NM_002264). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:500-1:5000IHC: 1:20-1:200IF: 1:10-1:100

Background :
KPNA1 represents karyopherin alpha 1 (importin alpha 5)

References :
Moriyama T, Nagai M, Oka M, Ikawa M, Okabe M, Yoneda Y. Targeted disruption of one of the importin α family members leads to female functional incompetence in delivery. The FEBS journal. 278(9):1561-72. 2011.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel