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Name :
KRAS-2A-specific antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
KRAS-2A-specific Rabbit Polyclonal antibody. Positive IF detected in SH-SY5Y cells. Positive IHC detected in human lung cancer tissue, human colon cancer tissue. Positive FC detected in HeLa cells. Positive WB detected in SH-SY5Y cells. Observed molecular weight by Western-blot: 21-24 kDa

Tested applications :
ELISA, WB, IHC, FC, IF

Species reactivity :
Human; other species not tested.

Alternative names :
C K RAS antibody; c Ki ras antibody; GTPase KRas antibody; K Ras 2 antibody; K RAS2A antibody; K RAS2B antibody; K RAS4A antibody; K RAS4B antibody; KI RAS antibody; KRAS antibody; KRAS1 antibody; KRAS2 antibody; KRAS2A antibody; KRAS2B speicifc antibody; KRAS4A antibody; Krasa antibody; Krasb antibody; NS3 antibody; RASK2 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of Peptide (Accession Number: NM_033360). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200IF: 1:50-1:500

Background :
RAS (derived from ‘RAt Sarcoma’ virus) gene family includes KRAS, HRAS, and NRAS. These genes encode very similar 21 kDa proteins and are homologs of rodent sarcoma virus genes that have transforming abilities. KRAS has two isoforms, 2A and 2B. This antibody is specific for KRAS-2A, which also named as KRAS-4A .

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: Gardos- Channel