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Name :
KRAS-2B-specific antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
KRAS-2B-specific Rabbit Polyclonal antibody. Positive IHC detected in human pancreas cancer tissue, human colon cancer tissue. Positive IF detected in HepG2 cells. Positive FC detected in HepG2 cells. Positive WB detected in mouse brain tissue, MCF7 cells, mouse kidney tissue. Observed molecular weight by Western-blot: 21 kDa

Tested applications :
ELISA, WB, IF, IHC, FC

Species reactivity :
Human, Mouse; other species not tested.

Alternative names :
C K RAS antibody; c Ki ras antibody; GTPase KRas antibody; K Ras 2 antibody; K RAS2A antibody; K RAS2B antibody; K RAS4A antibody; K RAS4B antibody; KI RAS antibody; KRAS antibody; KRAS1 antibody; KRAS2 antibody; KRAS2B antibody; KRAS2B speicifc antibody; Krasa antibody; Krasb antibody; NS3 antibody; RASK2 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of Peptide (Accession Number: NM_004985). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200IF: 1:10-1:100

Background :
RAS gene family encodes very similar 21KD proteins and are homologs of rodent sarcoma virus genes that have transforming abilities. KRAS has two isoforms, 2A and 2B. This antibody is specific for KRASB.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel