Name :
KRT33B antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
KRT33B Rabbit Polyclonal antibody. Positive WB detected in MCF7 cells, human brain tissue. Positive IHC detected in human prostate cancer. Observed molecular weight by Western-blot: 46 kDa
Tested applications :
ELISA, WB, IHC
Species reactivity :
human; other species not tested.
Alternative names :
KRT33B antibody; hHa3 II antibody; KRTHA3A antibody; keratin 33B antibody; Ha 3II antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of KRT33B recombinant protein (Accession Number: NM_002279). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200
Background :
Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells. Keratin expression is highly regulated, tissue specific, and varies according to cell-state. Type I keratins consist of acidic, low molecular weight proteins with MW ranging from 40 kDa (KRT19) to 64 kDa (KRT9). Type 2 keratins consist of basic or neutral, high molecular weight proteins with MW from 52 kDa (KRT8) to 67 kDa (KRT18). Keratin 33 belongs to type I keratin and is found in hair and nails. There are two isoforms of this protein, encoded by two separate genes, KRTHA3A and KRTHA3B.
References :
Ma YM, Wu KJ, Dang Q. Testosterone regulates keratin 33B expression in rat penis growth through androgen receptor signaling. Asian journal of andrology. 16(6):817-23. 2014.
Related websites: https://www.medchemexpress.com/antibodies.html
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