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Name :
KRT34 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
KRT34 Rabbit Polyclonal antibody. Positive IHC detected in human skin tissue. Positive IF detected in HepG2 cells. Positive WB detected in HeLa cells, A375 cells, A431 cells, HepG2 cells, L02 cells, mouse skin tissue. Observed molecular weight by Western-blot: 49 kDa

Tested applications :
ELISA, IHC, IF, WB

Species reactivity :
Human, Mouse; other species not tested.

Alternative names :
Ha 4 antibody; HA4 antibody; Hair keratin antibody; type I Ha4 antibody; hHa4 antibody; HKA4 antibody; K34 antibody; keratin 34 antibody; Keratin antibody; type I cuticular Ha4 antibody; KRT34 antibody; KRTHA4 antibody

Immunogen :
Human KRT34 Recombinant protein (GST tag)

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of KRT34 recombinant protein (Accession Number: NM_021013). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200IF: 1:10-1:100

Background :
Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells. Keratin expression is highly regulated, tissue specific, and varies according to cell-state. Type I keratins consist of acidic, low molecular weight proteins with MW ranging from 40 kDa (KRT19) to 64 kDa (KRT9). Type 2 keratins consist of basic or neutral, high molecular weight proteins with MW from 52 kDa (KRT8) to 67 kDa (KRT18). KRT 34 is a type I keratin.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel