Name :
KRT6B antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
KRT6B Rabbit Polyclonal antibody. Positive IP detected in mouse skin tissue. Positive WB detected in mouse skin tissue, A431 cells. Positive IHC detected in human cervix tissue, human oesophagus tissue, human tonsil tissue. Observed molecular weight by Western-blot: 60 kDa
Tested applications :
ELISA, WB, IHC, IP
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
CK 6B antibody; CK6B antibody; Cytokeratin 6B antibody; K6B antibody; keratin 6B antibody; KRT6B antibody; KRTL1 antibody; PC2 antibody; Type II keratin Kb10 antibody
Immunogen :
Human KRT6B Recombinant protein (GST tag)
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of KRT6B recombinant protein (Accession Number: NM_005555). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:200-1:2000IHC: 1:20-1:200
Background :
Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. Keratin 6 is a type II keratin. It is used as marker for epidermal hyperproliferation and differentiation. Three keratin 6 isoforms were found, ketatin 6A,6B and 6C. They share more than 99% identical DNA sequence.
References :
Cui CY, Klar J, Georgii-Heming P. Frizzled6 deficiency disrupts the differentiation process of nail development. The Journal of investigative dermatology. 133(8):1990-7. 2013.
Related websites: https://www.medchemexpress.com/antibodies.html
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