Name :
Kynurenine 3 monooxygenase antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Kynurenine 3 monooxygenase Mouse Monoclonal antibody. Positive WB detected in HEK-293 cells, HeLa cells, human heart tissue, mouse brain tissue, SKOV-3 cells. Positive IHC detected in human heart tissue, human liver tissue, human ovary tissue, human skin tissue. Positive IF detected in C6 cells. Observed molecular weight by Western-blot: 56 kDa
Tested applications :
ELISA, IHC, IF, WB
Species reactivity :
Human, Mouse, Rat; other species not tested.
Alternative names :
dJ317G22.1 antibody; KMO antibody; Kynurenine 3 hydroxylase antibody; Kynurenine 3 monooxygenase antibody
Immunogen :
Human KMO Recombinant protein (GST tag)
Isotype :
Mouse IgG1
Preparation :
This antibody was obtained by immunization of Kynurenine 3 monooxygenase recombinant protein (Accession Number: BC005297). Purification method: Caprylic acid/ammonium sulfate precipitation.
Clonality :
Monoclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200IF: 1:10-1:100
Background :
KMO(Kynurenine 3-monooxygenase) is an NADPH-dependent flavin monooxygenase, catalysing the hydroxylation of the L-tryptophan metabolite L-kynurenine to form L-3-hydroxykynurenine. KMO is a membrane protein located on the outer membrane of mitochondria. Tissue distribution studies have revealed that, in rats, highest enzyme activity is found in kidney and liver, with brain having the least activity in comparison to peripheral organs(PMID: 9237672).
References :
Bosnyák E, Kamson DO, Guastella AR. Molecular imaging correlates of tryptophan metabolism via the kynurenine pathway in human meningiomas. Neuro-oncology. 17(9):1284-92. 2015.
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
Phospho-STAT1(S727)Rabbit mAb In stock
MAPK14 Mouse mAb Protocol
FIP200 Antibody: FIP200 Antibody is a non-conjugated and Mouse origined monoclonal antibody about 183 kDa, targeting to FIP200. It can be used for WB assays with tag free, in the background of Human, Mouse.
