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Name :
LACTB antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
LACTB Rabbit Polyclonal antibody. Positive IHC detected in human liver. Positive WB detected in human heart tissue, HeLa cells. Observed molecular weight by Western-blot: 55kd

Tested applications :
ELISA, WB, IHC

Species reactivity :
human, mouse, rat; other species not tested.

Alternative names :
LACTB antibody; MRPL56 antibody; lactamase antibody; beta antibody; G24 antibody; FLJ14902 antibody

Immunogen :
Human LACTB Recombinant protein (His tag)

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of LACTB recombinant protein (Accession Number: NM_032857). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:1000-1:10000IHC: 1:20-1:200

Background :
LACTB is also named as MRPL56,whic is a component of the large subunit of the mitochondrial ribosome that is encoded by the nuclear genome.LACTB is a mammalian active-site serine protein that has evolved from a bacterial penicillin-binding protein.It promotes intramitochondrial membrane organization and micro-compartmentalization through polymerization(PMID:19858488). Northern blot analysis of mouse tissues detected expression at high levels in liver, heart, and skeletal muscle, with lower levels in kidney, testis, brain, lung, and spleen(PMID:11707067).This antibody is specific to LACTB.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel