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Name :
Lactoferrin antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
Lactoferrin Rabbit Polyclonal antibody. Positive WB detected in HEK-293 cells, human pancreas tissue. Positive IP detected in HeLa cells. Positive IHC detected in human liver tissue, human prostate hyperplasia tissue. Observed molecular weight by Western-blot: 51 kDa

Tested applications :
ELISA, IHC, WB, IP

Species reactivity :
Human; other species not tested.

Alternative names :
GIG12 antibody; HLF2 antibody; Lactoferrin antibody; lactotransferrin antibody; LTF antibody; Talalactoferrin antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of Lactoferrin recombinant protein (Accession Number: NM_002343). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000IP: 1:200-1:2000IHC: 1:20-1:200

Background :
LTF(Lactotransferrin) is also named as GIG12, LF and belongs to the transferrin family. It is an iron binding transport protein which can bind two atoms of ferric iron in association with the binding of an anion, usually bicarbonate. LTF is also an important protein component of the innate immune system that is broadly distributed within the body fluids. It can contribute to the activation of both the innate and adaptive immune responses by promoting the recruitment of leukocytes and activation of dendritic cells(PMID:18453607). This protein has 2 isoforms produced by alternative promoter usage. The human LTF can be isolated two fragments, an N-terminal tryptic fragment having an Mr of 30 kDa and a C-terminal tryptic fragment having an Mr of 50 kDa by a mild tryptic digest(PMID:3790094).

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel