Name :
LASP1 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
LASP1 Rabbit Polyclonal antibody. Positive WB detected in MCF7 cells, MDA-MB-453s cells, mouse brain tissue, PC-3 cells, SGC-7901 cells. Positive IP detected in rat brain tissue. Positive IF detected in Hela cells. Positive IHC detected in human breast cancer tissue, human colon cancer tissue. Observed molecular weight by Western-blot: 38-40 kDa
Tested applications :
ELISA, WB, IF, IHC, IP
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
Lasp 1 antibody; LASP1 antibody; LIM and SH3 domain protein 1 antibody; LIM and SH3 protein 1 antibody; MLN 50 antibody; MLN50 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of LASP1 recombinant protein (Accession Number: NM_006148). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:1000-1:10000IP: 1:500-1:5000IHC: 1:20-1:200IF: 1:10-1:100
Background :
LASP1 represents LIM and SH3 protein 1
References :
Zhang H, Li Z, Chu B. Upregulated LASP-1 correlates with a malignant phenotype and its potential therapeutic role in human cholangiocarcinoma. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 2016. Li Z, Chen Y, Wang X. LASP-1 induces proliferation, metastasis and cell cycle arrest at the G2/M phase in gallbladder cancer by down-regulating S100P via the PI3K/AKT pathway. Cancer letters. 372(2):239-50. 2016. Zeng Z, Bo H, Gong Z. AFAP1-AS1, a long noncoding RNA upregulated in lung cancer and promotes invasion and metastasis. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 2015. Du YY, Zhao LM, Chen L. The tumor-suppressive function of miR-1 by targeting LASP1 and TAGLN2 in esophageal squamous cell carcinoma. Journal of gastroenterology and hepatology. 31(2):384-93. 2016. Bo H, Gong Z, Zhang W. Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma. Oncotarget. 6(24):20404-18. 2015.
Related websites: https://www.medchemexpress.com/antibodies.html
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