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Name :
LAT2 Polyclonal Antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
Polyclonal antibody to LAT2

Tested applications :
WB

Species reactivity :
Human

Alternative names :
LAT2 antibody; HSPC046 antibody; LAB antibody; NTAL antibody; WBSCR15 antibody; WBSCR5 antibody; WSCR5 antibody; linker for activation of T-cells family member 2 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
Antigen: A synthetic Peptide of human LAT2

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide, pH7.3.

Storage instructions :
Store at 4℃. Avoid freeze / thaw cycles.

Applications :
WB 1:500 – 1:1000

Background :
Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel