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Name :
LCE1B antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
LCE1B Rabbit Polyclonal antibody. Positive WB detected in A375 cells, mouse skin tissue, rat skin tissue. Positive IHC detected in human skin tissue, human oesophagus tissue. Positive IF detected in A375 cells. Observed molecular weight by Western-blot: 10-12 kDa

Tested applications :
ELISA, WB, IHC, IF

Species reactivity :
Human, Mouse, Rat; other species not tested.

Alternative names :
late cornified envelope 1B antibody; Late envelope protein 2 antibody; LCE1B antibody; LEP2 antibody; SPRL2A antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of LCE1B recombinant protein (Accession Number: NM_178349). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200IF: 1:20-1:200

Background :
Human LCE1B (Late cornified envelope protein 1B), also named late envelope protein 2 (LEP2), is located at human Chromosome1q21 which contains multiple LCE clusters. LCE1B gene is predicated to encode a 118-aa protein, and is currently evidenced at transcript level. Its expression was skin-specific and was readily detected in adult trunk skin, adult arm skin, fetal skin, penal skin, vulva, esophagus and tongue (PMID: 15854049). LCE genes respond to environmental stimuli such as calcium levels and ultraviolet (UV) light, however, LCE groups have distinct functions (PMID: 15854049).

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel