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Name :
LCK antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
LCK Mouse Monoclonal antibody. Positive WB detected in Jurkat cell, Jurkat cells. Observed molecular weight by Western-blot: 50-55 kDa

Tested applications :
ELISA, WB

Species reactivity :
Human; other species not tested.

Alternative names :
LCK antibody; LSK antibody; p56 LCK antibody; p56lck antibody; pp58lck antibody; Protein YT16 antibody; Proto oncogene Lck antibody; Tyrosine protein kinase Lck antibody; YT16 antibody

Immunogen :
Human LCK Recombinant protein (His tag)

Isotype :
Mouse IgG1

Preparation :
This antibody was obtained by immunization of LCK recombinant protein (Accession Number: BC013200). Purification method: Protein G purified.

Clonality :
Monoclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000

Background :
LCK(Lymphocyte cell-specific protein-tyrosine kinase) is also named as LSK,p56-LCK and a nonreceptor protein-tyrosine kinase of the SRConcogene family that is involved in transduction of T-cell receptor-mediated activation.It is implicated in the control of lymphocyte growth by virtue of its overexpression in some lymphoid malignancies and its transforming activity in heterologous systems(PMID:2784463).It has 3 isoforms produced by alternative splicing.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel