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Name :
LDOC1 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
LDOC1 Rabbit Polyclonal antibody. Positive WB detected in Transfected HEK-293 cells. Observed molecular weight by Western-blot: 23 kDa

Tested applications :
ELISA, WB

Species reactivity :
Human, Mouse; other species not tested.

Alternative names :
LDOC1 antibody; Mar7 antibody; Mart7 antibody; Protein LDOC1 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of LD℃1 recombinant protein (Accession Number: NM_012317). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:1000

Background :
LDoc1 contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. LDoc1 localizes to the nucleus and is down-regulated in some cancer cell lines. LDoc1 regulates the transcriptional response mediated by the nuclear factor B (NF-kappa B). The gene encoding LDoc1 protein has been proposed as a tumor suppressor gene which may have an important role in the development and/or progression of some cancers.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel