Name :
LFNG Polyclonal Antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Polyclonal antibody to LFNG
Tested applications :
WB, IHC, FC
Species reactivity :
Human
Alternative names :
LFNG antibody; SCDO3 antibody; beta-1,3-N-acetylglucosaminyltransferase lunatic fringe antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
Antigen: A synthetic peptide of human LFNG
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide, pH7.3.
Storage instructions :
Store at 4℃. Avoid freeze / thaw cycles.
Applications :
WB 1:500 – 1:1000IHC 1:50 – 1:100FC 1:20 – 1:50
Background :
Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1 (By similarity). Decreases the binding of JAG1 to NOTCH2 but not that of DLL1. Essential mediator of somite segmentation and patterning (By similarity).
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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