Name :
LGR4 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
LGR4 Rabbit Polyclonal antibody. Positive IHC detected in human small intestine tissue.
Tested applications :
ELISA, IHC
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
G protein coupled receptor 48 antibody; GPR48 antibody; LGR4 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of LGR4 recombinant protein (Accession Number: NM_001346432). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: IHC: 1:20-1:200
Background :
LGR4, also known as GPR48, is a membrane of the leucine-rich GPCR family. LGR4 is composed of a large NH2-terminal extracellular domain containing 18 LRRs, the seven membrane-spanning segments, and a COOH-terminal intracellular domain. LGR4 is a receptor for R-spondins that potentiates the canonical Wnt signaling pathway and is involved in the formation of various organs. It has also been shown that LGR4 regulates cyclic AMP/protein kinase A (PKA) signalling. (PMID: 23756652; 17178856; 24212090)
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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