Name :
Anti-C3 Rabbit antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
C3 Rabbit monoclonal antibody
Tested applications :
WB
Species reactivity :
Human
Alternative names :
Immunogen :
Isotype :
Rabbit IgG
Preparation :
Antigen: A synthetic peptide of human C3
Clonality :
Monoclonal
Formulation :
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage instructions :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
Applications :
WB: 1/1000
Background :
Swiss-Prot Acc.P01024.C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a chemoattractant for neutrophils . It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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