Name :
LGR5 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
LGR5 Rabbit Polyclonal antibody. Positive IHC detected in human small intestine tissue, human colon cancer tissue, human colon tissue, human liver cancer tissue.
Tested applications :
ELISA, IHC
Species reactivity :
Human; other species not tested.
Alternative names :
FEX antibody; G protein coupled receptor 49 antibody; G protein coupled receptor 67 antibody; GPR49 antibody; GPR67 antibody; GRP49 antibody; HG38 antibody; LGR5 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of LGR5 recombinant protein (Accession Number: NM_003667). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: IHC: 1:20-1:200
Background :
LGR5, also named as GPR49, GPR67 and HG38, belongs to the G-protein coupled receptor 1 family. It is an orphan receptor. LGR5 is a stem cell marker of the intestinal epithelium and the hair follicule. It is a target gene of Wnt signaling.
References :
Wang Y, Jiang CQ, Fan LF. Correlation of Musashi-1, Lgr5, and pEGFR expressions in human small intestinal adenocarcinomas. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 36(8):6075-82. 2015. Vieira GC, Chockalingam S, Melegh Z. LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma. Oncotarget. 6(37):40053-67. 2015.
Related websites: https://www.medchemexpress.com/antibodies.html
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