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Name :
LGR6 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
LGR6 Rabbit Polyclonal antibody. Positive WB detected in mouse testis tissue, human brain tissue, mouse ovary tissue, PC-3 cells. Positive IHC detected in human testis tissue, human ovary tissue, human skin tissue, human spleen tissue. Positive FC detected in HeLa cells. Observed molecular weight by Western-blot: 104 kDa

Tested applications :
ELISA, IHC, WB, FC

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
FLJ14471 antibody; GPCR antibody; LGR6 antibody; VTS20631 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of LGR6 recombinant protein (Accession Number: NM_021636). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:1000IHC: 1:20-1:200

Background :
LGR6 (Leucine-rich repeat-containing G-protein coupled receptor 6) is a seven-transmembrane protein. LGR6 is a high affinity receptor of R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. It potentially functions as a tumor suppressor. (PMID: 20223988; 20417836; 22615920)

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel