Name :
LGR6 Polyclonal Antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Polyclonal antibody to LGR6
Tested applications :
WB
Species reactivity :
Human, Rat
Alternative names :
LGR6 antibody; GPCR antibody; VTS20631 antibody; leucine-rich repeat-containing G-protein coupled receptor 6 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
Antigen: A synthetic peptide corresponding to a sequence within amino acids 700-800 of human LGR6 (NP_001017404.1).
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage instructions :
Store at -20℃. Avoid freeze / thaw cycles.
Applications :
WB 1:500 – 1:2000
Background :
Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
Alexa Fluor® 647-conjugated AffiniPure Goat Anti-Rabbit IgG H&L Biological Activity
Histone H3 (acetyl K14) Rabbit mAb medchemexpress
Cytokeratin 5 Antibody: Cytokeratin 5 Antibody is an unconjugated, approximately 62 kDa, rabbit-derived, anti-Cytokeratin 5 monoclonal antibody. Cytokeratin 5 Antibody can be used for: WB, IHC-P, IF-Tissue, IF-Cell, FC expriments in human, mouse, rat background without labeling.
