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Name :
LHCGR antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
LHCGR Rabbit Polyclonal antibody. Positive WB detected in mouse testis tissue, mouse ovary tissue. Observed molecular weight by Western-blot: 100kd

Tested applications :
ELISA, WB

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
FLJ41504 antibody; LCGR antibody; LGR2 antibody; LH/CG R antibody; LH/CGR antibody; LHCGR antibody; LHR antibody; LHRHR antibody; LSH R antibody; Luteinizing Hormone Receptor antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of Peptide (Accession Number: NM_000233). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000

Background :
LHCGR, also named as LCGR, LGR2, LHRHR LHR and LSHR, belongs to the G-protein coupled receptor 1 family and FSH/LSH/TSH subfamily. LHCGR is a receptor for lutropin-choriogonadotropic hormone. The activity of LHCGR is mediated by G proteins which activate adenylate cyclase. Defects in LHCGR are a cause of familial male precocious puberty (FMPP). Defects in LHCGR are a cause of Leydig cell hypoplasia (LCH).

References :
Nozawa K, Nagaoka K, Zhang H. Neonatal exposure to 17α-ethynyl estradiol affects ovarian gene expression and disrupts reproductive cycles in female rats. Reproductive toxicology (Elmsford, N.Y.). 46:77-84. 2014. Ball CB, Rodriguez KF, Stumpo DJ. The RNA-binding protein, ZFP36L2, influences ovulation and oocyte maturation. PloS one. 9(5):e97324. 2014.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel