Name :
LIFR antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
LIFR Rabbit Polyclonal antibody. Positive IP detected in mouse skeletal muscle tissue. Positive WB detected in human skeletal muscle tissue, mouse skeletal muscle tissue. Positive FC detected in HeLa cells. Positive IHC detected in human skeletal muscle tissue, human kidney tissue, human placenta tissue. Observed molecular weight by Western-blot: 190 kDa
Tested applications :
ELISA, WB, IHC, IP, FC
Species reactivity :
Human, Mouse; other species not tested.
Alternative names :
CD118 antibody; FLJ98106 antibody; FLJ99923 antibody; LIF R antibody; LIF receptor antibody; LIFR antibody; SJS2 antibody; STWS antibody; SWS antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of LIFR recombinant protein (Accession Number: XM_011514040). Purification method: Antigen Affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IP: 1:500-1:5000IHC: 1:20-1:200
Background :
LIFR, also known as CD118, is a subunit of a receptor for leukemia inhibitory factor (LIF). LIF is a pleiotropic cytokine of the interleukin-6 family which affects the differentiation, survival, and proliferation of a wide variety of cells in the adult and the embryo. LIFR is the low-affinity binding chain that, together with the high-affinity converter subunit gp130, forms a high-affinity receptor complex that mediates the action of LIF. The high-affinity complex also binds a related cytokine, oncostatin M (PMID: 8999038). LIFR has also been identified as a breast cancer metastasis suppressor that functions through the HIPPO-YAP pathway (PMID: 23001183).
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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