Name :
LIN28 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
LIN28 Mouse Monoclonal antibody. Positive WB detected in NCCIT cell. Observed molecular weight by Western-blot: 28 kDa
Tested applications :
ELISA, WB
Species reactivity :
Human; other species not tested.
Alternative names :
CSDD1 antibody; FLJ12457 antibody; LIN 28 antibody; lin 28 homolog (C. elegans) antibody; Lin 28A antibody; LIN28 antibody; Lin28A antibody; Protein lin 28 homolog A antibody; ZCCHC1 antibody
Immunogen :
Isotype :
Mouse IgG1
Preparation :
This antibody was obtained by immunization of LIN28 recombinant protein (Accession Number: NM_024674). Purification method: Protein G purified.
Clonality :
Monoclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000
Background :
LIN28 is one of the four key human factors (ocT4, SOX2, NANOG and LIN28) used to reprogram human fibroblasts to an embryonic stem (ES) cell-like state known as the induced pluripotent stem (Ips) cell. Lin28 is a marker of undifferentiated human embryonic stem cells and a cytoplasmic Mrna-binding protein that binds to and enhances the translation of the IGF2 Mrna. LIN28 has also been shown to bind to the let-7 pre-miRNA and block production of the mature let-7 microRNA in mouse embryonic stem cells.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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