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Name :
LIV-1 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
LIV-1 Rabbit Polyclonal antibody. Positive WB detected in HeLa cells. Observed molecular weight by Western-blot: 100kd

Tested applications :
ELISA, WB

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
LIV 1 antibody; LIV1 antibody; SLC39A6 antibody; Zinc transporter ZIP6 antibody; ZIP 6 antibody; ZIP6 antibody; Zrt and Irt like protein 6 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of LIV-1 recombinant protein (Accession Number: NM_001099406). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000

Background :
SLC39A6 represents solute carrier family 39 (zinc transporter), member 6

References :
Wu C, Li D, Jia W. Genome-wide association study identifies common variants in SLC39A6 associated with length of survival in esophageal squamous-cell carcinoma. Nature genetics. 45(6):632-8. 2013. Cui XB, Shen YY, Jin TT. SLC39A6: a potential target for diagnosis and therapy of esophageal carcinoma. Journal of translational medicine. 13:321. 2015. Lian J, Jing Y, Dong Q. miR-192, a prognostic indicator, targets the SLC39A6/SNAIL pathway to reduce tumor metastasis in human hepatocellular carcinoma. Oncotarget. 7(3):2672-83. 2016.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel