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Name :
LMNB2 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
LMNB2 Rabbit Polyclonal antibody. Positive FC detected in HEK-293T cells. Positive IF detected in HepG2 cells, SH-SY5Y cells. Positive IHC detected in human colon cancer tissue. Positive IP detected in Jurkat cells. Positive WB detected in Jurkat cells, BxPC-3 cells, HEK-293 cells, HeLa cells, HL-60 cells, MCF7 cells, mouse brain tissue. Observed molecular weight by Western-blot: 66-68kd

Tested applications :
ELISA, WB, IHC, IF, FC, IP

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
LAMB2 antibody; lamin B2 antibody; LMN2 antibody; LMNB2 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of LMNB2 recombinant protein (Accession Number: BC006551). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:1000-1:10000IP: 1:200-1:2000IHC: 1:20-1:200IF: 1:10-1:100

Background :
LMNB2 represents lamin B2

References :
Kuga T, Nie H, Kazami T. Lamin B2 prevents chromosome instability by ensuring proper mitotic chromosome segregation. Oncogenesis. 3:e94. 2014. Kuga T, Nozaki N, Matsushita K, Nomura F, Tomonaga T. Phosphorylation statuses at different residues of lamin B2, B1, and A/C dynamically and independently change throughout the cell cycle. Experimental cell research. 316(14):2301-12. 2010.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel