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Name :
LRRTM2 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
LRRTM2 Rabbit Polyclonal antibody. Positive WB detected in mouse spinal cord tissue. Observed molecular weight by Western-blot: 59 kDa

Tested applications :
ELISA, WB

Species reactivity :
Human, Mouse; other species not tested.

Alternative names :
FLJ76283 antibody; FLJ99831 antibody; KIAA0416 antibody; LRRN2 antibody; LRRTM2 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of LRRTM2 recombinant protein (Accession Number: NM_015564). Purification method: Antigen Affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000

Background :
Leucine-rich repeat transmembrane proteins (LRRTMs) are synaptic cell adhesion molecules. LRRTMs are highly localized in the postsynaptic density and play various roles in the formation, maturation, and function of synapses (PMID: 25951919). LRRTM2 acts as a post-synaptic ligand of Neurexins. LRRTM2 regulates excitatory synapse development and function in the vertebrate nervous system (PMID: 20064387).

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel