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Name :
LSM4 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
LSM4 Rabbit Polyclonal antibody. Positive IHC detected in human lung cancer tissue. Positive WB detected in MCF7 cells, human placenta tissue, MDA-MB-231 cells. Observed molecular weight by Western-blot: 15 kDa

Tested applications :
ELISA, WB, IHC

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
Glycine rich protein antibody; GRP antibody; LSM4 antibody; YER112W antibody

Immunogen :
Human LSM4 Recombinant protein (GST tag)

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of LSM4 recombinant protein (Accession Number: NM_012321). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200

Background :
Sm-like proteins, such as LSM4, were identified in a variety of organisms based on sequence homology with the Sm protein family. Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing

References :
Berg MG, Wan L, Younis I. A quantitative high-throughput in vitro splicing assay identifies inhibitors of spliceosome catalysis. Molecular and cellular biology. 32(7):1271-83. 2012.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel