Name :
Acetyl-Histone H4-K12 pAb
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Polyclonal antibody to Acetyl-Histone H4-K12
Tested applications :
WB, IHC, IF
Species reactivity :
Human, Mouse, Rat, Other (Wide Range)
Alternative names :
HIST1H4B antibody; H4/I antibody; H4FI antibody; histone H4 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
Antigen: A synthetic acetylated peptide around K12 of human Histone H4 (NP_001029249.1).
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage instructions :
Store at -20℃. Avoid freeze / thaw cycles.
Applications :
WB 1:500 – 1:2000IHC 1:50 – 1:200IF 1:50 – 1:200
Background :
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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