Name :
LTA4H antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
LTA4H Rabbit Polyclonal antibody. Positive IHC detected in human skin tissue, human brain tissue, human heart tissue, human kidney tissue, human lung tissue, human ovary tissue, human placenta tissue, human spleen tissue, human testis tissue. Positive IP detected in HEK-293 cells. Positive WB detected in HEK-293 cells, Jurkat cells. Observed molecular weight by Western-blot: 57-70 kDa
Tested applications :
ELISA, IHC, WB, IP
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
Leukotriene A 4 hydrolase antibody; Leukotriene A(4) hydrolase antibody; leukotriene A4 hydrolase antibody; LTA 4 hydrolase antibody; LTA4 antibody; LTA4H antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of LTA4H recombinant protein (Accession Number: NM_000895). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:200-1:2000IHC: 1:20-1:200
Background :
LTA4H(Leukotriene A-4 hydrolase) is also named as LTA4 and belongs to the peptidase M1 family. It is essential for the conversion of LTA4 to LTB4, an inflammatory lipid mediator(PMID:10601658). LTA4H also possesses aminopeptidase activity that it can degrade PGP, which is a biomarker for chronic obstructive pulmonary disease and is implicated in neutrophil persistence in the lung(PMID:20813919). This protein has 4 isoforms produced by alternative splicing with the MW of 69, 59, 57, 67 kDa.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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