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Name :
LXN antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
LXN Rabbit Polyclonal antibody. Positive IP detected in mouse lung tissue. Positive WB detected in mouse lung tissue, human brain tissue, mouse ovary tissue, mouse pancreas tissue. Observed molecular weight by Western-blot: 26kd

Tested applications :
ELISA, WB, IP

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
ECI antibody; latexin antibody; LXN antibody; Protein MUM antibody; TCI antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of LXN recombinant protein (Accession Number: NM_020169). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:200-1:2000

Background :
Latexin, also named as LTXN, LXN, ECI, MUM and TCI, is hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. It may function as a neuroprotective mechanism against tau toxicity.

References :
Yata K, Oikawa S, Sasaki R. Astrocytic neuroprotection through induction of cytoprotective molecules; a proteomic analysis of mutant P301S tau-transgenic mouse. Brain research. 1410:12-23. 2011.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel