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Name :
LZTFL1 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
LZTFL1 Rabbit Polyclonal antibody. Positive IHC detected in human heart tissue, human testis tissue. Positive IP detected in HEK-293 cells. Positive WB detected in human testis tissue, HEK-293 cells. Observed molecular weight by Western-blot: 35 kDa

Tested applications :
ELISA, WB, IHC, IP

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
FLJ36386 antibody; LZTFL1 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of LZTFL1 recombinant protein (Accession Number: NM_020347). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000IP: 1:200-1:2000IHC: 1:20-1:200

Background :
LZTFL1 belongs to the LZTFL1 family. It is an important regulator of BBSome ciliary trafficking and hedgehog signaling. LZTFL1 regulates Ciliary Trafficking of the BBSome and Smoothened.(PMID:22072986)

References :
Eguether T, San Agustin JT, Keady BT. IFT27 links the BBSome to IFT for maintenance of the ciliary signaling compartment. Developmental cell. 31(3):279-90. 2014.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel