Name :
MACF1 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
MACF1 Rabbit Polyclonal antibody. Positive WB detected in Transfected HEK-293 cells. Positive IHC detected in human prostate cancer tissue, human heart tissue, human skeletal muscle tissue. Positive IF detected in RPE cells, NIH/3T3 cells.
Tested applications :
ELISA, IHC, IF, WB
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
620 kDa actin binding protein antibody; ABP620 antibody; ACF7 antibody; FLJ45612 antibody; FLJ46776 antibody; KIAA0465 antibody; KIAA1251 antibody; MACF antibody; MACF1 antibody; Macrophin 1 antibody; OFC4 antibody; Trabeculin alpha antibody
Immunogen :
Human MACF1 Recombinant protein (GST tag)
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of MACF1 recombinant protein (Accession Number: BC007330). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200IF: N/A
Background :
MACF1, also called ACF7 (actin crosslinking family 7), is a member of the spectraplakin family and is a ubiquitously expressed 614 kDa protein. This protein facilitates actin-microtubule interactions at the cell periphery and couples the microtubule network to cellular junctions. It displays a conserved role in membrane protrusion formation during evolution. The two major MACF1 isoforms characterized to date, MACF1a and MACF1b, result from alternative splicing. Both proteins contain N-terminal actin-binding domains (ABD), followed by plakin domains, extended spectrin repeat domains, EF-hand motifs, and C-terminal microtubule-binding domains (MTBDs). MACF1 is expressed in numerous tissue, including the skin, brain, skeletal muscle, and heart.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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