Name :
MAD2L1BP antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
MAD2L1BP Rabbit Polyclonal antibody. Positive IF detected in A431 cells. Positive IHC detected in human skin tissue, human colon tissue. Positive WB detected in HeLa cells, K-562 cells. Observed molecular weight by Western-blot: 34kd
Tested applications :
ELISA, WB, IHC, IF
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
Caught by MAD2 protein antibody; CMT2 antibody; KIAA0110 antibody; MAD2L1 binding protein antibody; MAD2L1BP antibody; RP1 261G23.6 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of MAD2L1BP recombinant protein (Accession Number: NM_014628). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200IF: 1:20-1:200
Background :
MAD2L1BP, also named as CMT2 and KIAA0110, belongs to the MAD2L1BP family. It may function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex. MAD2L1BP interacts with the spindle checkpoint and coordinates cell cycle events in late mitosis. MAD2L1BP may play an active role to remove MAD2 from p55CDC and tether MAD2 for silencing the checkpoint.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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